Sim, S M; Choo, W Y; Ng, C J
Are our new medical graduates ready to prescribe? Journal Article
In: Med Educ, vol. 43, no. 5, pp. 492, 2009, ISSN: 0308-0110.
@article{RN16034,
title = {Are our new medical graduates ready to prescribe?},
author = {S M Sim and W Y Choo and C J Ng},
doi = {10.1111/j.1365-2923.2009.03352.x},
issn = {0308-0110},
year = {2009},
date = {2009-01-01},
journal = {Med Educ},
volume = {43},
number = {5},
pages = {492},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Moy, F M; Johari, S; Ismail, Y; Mahad, R; Tie, F H; Ismail, W A Wan
Breakfast Skipping and Its Associated Factors among Undergraduates in a Public University in Kuala Lumpur Journal Article
In: Malays J Nutr, vol. 15, no. 2, pp. 165-74, 2009, ISSN: 1394-035X (Print) 1394-035x.
@article{RN14541,
title = {Breakfast Skipping and Its Associated Factors among Undergraduates in a Public University in Kuala Lumpur},
author = {F M Moy and S Johari and Y Ismail and R Mahad and F H Tie and W A Wan Ismail},
issn = {1394-035X (Print)
1394-035x},
year = {2009},
date = {2009-01-01},
journal = {Malays J Nutr},
volume = {15},
number = {2},
pages = {165-74},
abstract = {An analytical cross-sectional study was conducted in a public university in Kuala Lumpur among a random sample of 2665 undergraduates. The objective was to study the prevalence of breakfast skipping and its associated factors. Data collection was conducted via a self-administered pre-tested questionnaire. There were 43.5% male respondents, with Malays being the majority (58.3%). The prevalence of breakfast skipping was 29.2 (95% CI: 27.3 - 30.3)%. The factors significantly associated with breakfast skipping (p\<0.05) were age, race, accommodation, faculty and skipping dinner. As the respondents' age increased, their risk of breakfast skipping was lower (OR: 0.95; 0.89 - 0.99). Malays (OR: 1.94; 1.48 - 2.54), Indians (OR: 1.70; 1.08 - 2.66), and students from the Sabah and Sarawak indigenous communities (OR: 2.13; 1.37 - 3.33) were more likely to skip breakfast compared to their Chinese counterparts. Respondents who stayed in their own houses were also less likely to skip breakfast compared to those staying in hostel with meals catered (OR: 2.32; 1.39 - 3.84), hostel with cafeteria (OR: 2.92; 1.74 - 4.91) or in rented houses (OR: 2.08; 1.25 - 3.46). Respondents majoring in Arts and Economics had 1.40 (1.07 - 1.82) times risk of breakfast skipping compared to those majoring in Life Sciences. Those who skipped dinner too had twice the odds (1.47 - 2.77) of breakfast skipping. In conclusion the prevalence of breakfast skipping among the undergraduates of this university was moderately high. Health awareness campaigns or introduction of healthy eating guidelines should be initiated for the undergraduates as well as food caterers in campus. The policy and pricing of catered food in campus should also be reviewed.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Tan, G H; Taib, N A; Choo, W Y; Teo, S H; Yip, C H
Clinical characteristics of triple-negative breast cancer: experience in an Asian developing country Journal Article
In: Asian Pac J Cancer Prev, vol. 10, no. 3, pp. 395-8, 2009, ISSN: 1513-7368.
@article{RN16031,
title = {Clinical characteristics of triple-negative breast cancer: experience in an Asian developing country},
author = {G H Tan and N A Taib and W Y Choo and S H Teo and C H Yip},
issn = {1513-7368},
year = {2009},
date = {2009-01-01},
journal = {Asian Pac J Cancer Prev},
volume = {10},
number = {3},
pages = {395-8},
abstract = {INTRODUCTION: Triple negative (TN) breast cancers are defined by a lack of expression of oestrogen, progesterone, and HER2 receptors. They tend to have a higher grade, with a poorer outcome compared to non-TN breast cancers. OBJECTIVE: The aim of this study is to determine the incidence of TN breast cancer in an Asian country consisting of Malays, Chinese and Indians, and to determine the factors associated with this type of breast cancer. RESULTS: The incidence of TN breast cancer in the University Malaya Medical Center is 17.6%. There is no significant difference amongst the Malays, Chinese and Indians. In bivariate analysis, TN breast cancer was significantly associated with younger age and Grade 3. However, in multivariate analysis using logistic regression, TN breast cancer was only associated with Grade 3. CONCLUSION: The incidence of TN breast cancer in our study is similar to other studies, and associated with a higher grade.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Nagaraj, Shyamala; Lee, Kiong-Hock; Tey, Nai-Peng; Ng, Chiu-Wan; Pala, Jean
Counting Ethnicity in Malaysia: the Complexity of Measuring Diversity* Journal Article
In: Malaysian Journal of Economic Studies, vol. 46, no. 1, pp. 5-32, 2009, ISSN: 15114554.
@article{RN14649,
title = {Counting Ethnicity in Malaysia: the Complexity of Measuring Diversity*},
author = {Shyamala Nagaraj and Kiong-Hock Lee and Nai-Peng Tey and Chiu-Wan Ng and Jean Pala},
url = {http://ezproxy.um.edu.my/docview/312320179?accountid=28930},
issn = {15114554},
year = {2009},
date = {2009-01-01},
journal = {Malaysian Journal of Economic Studies},
volume = {46},
number = {1},
pages = {5-32},
abstract = {Malaysia has long been concerned with the ethnic dimensions in society. A driver of government policy since the early 1970s, it is factored into the production of official statistics. Data on ethnicity is therefore very important for monitoring and strengthening public policies that seek to address ethnic imbalances. This paper examines the complexity of defining and measuring ethnicity across time and across different official documents. The paper highlights the difficulties in collecting ethnic data and shows how creative the data collection agencies have been over the years in defining and redefining ethnicity as Malaysian society and needs evolve. The experience of Malaysia indicates that not only does measurement of ethnic data support policy but that policy can also drive ethnic measurement in data. The discussion raises important questions on how ethnic groups have been defined, the purpose for which such data is gathered and how the data is gathered. The problem is not the data themselves but how they are used to formulate, implement and monitor policies. [PUBLICATION ABSTRACT]},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Tan, G H; Choo, W Y; Taib, N A; Yip, C H
Factors associated with HER2 overexpression in breast cancer: Experience in an Asian developing country Journal Article
In: Asian Pac J Cancer Prev, vol. 10, no. 5, pp. 837-40, 2009, ISSN: 1513-7368.
@article{RN16025,
title = {Factors associated with HER2 overexpression in breast cancer: Experience in an Asian developing country},
author = {G H Tan and W Y Choo and N A Taib and C H Yip},
issn = {1513-7368},
year = {2009},
date = {2009-01-01},
journal = {Asian Pac J Cancer Prev},
volume = {10},
number = {5},
pages = {837-40},
abstract = {INTRODUCTION: The HER2 gene is amplified in up to 30% of human breast cancers, leading to overexpression of the HER2 protein on the cell surface. Overexpression of HER2 is associated with a more aggressive cancer and hence a poorer overall survival. OBJECTIVE: To evaluate the association between clinico-pathological features and HER2 overexpression in breast cancer. METHODS: This is a retrospective study conducted in the Department of Surgery, University Malaya Medical Centre. The association between HER2 overexpression, determined by immunohistochemistry, and other clinicopathological factors was evaluated in 996 patients with newly diagnosed breast cancer treated from 2005 to 2007 using univariate and multivariate logistic regression. RESULTS: HER2 overexpression occurred in 30.3% of patients. On bivariate analysis, HER2 overexpression was inversely related to ER expression (p\<0.01) and PR expression (p\<0.01). This overexpression was associated with a higher tumour grade, lymphovascular positivity and infiltrating ductal carcinoma subtype. On multivariate analysis, HER2 overexpression was significantly associated with higher tumour grade (p= 0.018, CI 1.25-11.04), PR negativity (p= 0.002, CI 0.30-0.77) and lymphovascular positivity (p= 0.042, CI 1.01-2.12). CONCLUSIONS: HER2 overexpression was observed in 30.3% of Malaysian female breast cancer patients. This group of patients represents a more aggressive subtype of breast cancer with higher tumour grade, PR negativity and lymphovascular positivity. No significant relationship was established between HER2 overexpression and age, race, lymph node, ER, pathology subtype and stage of disease from this study.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Su, T T; Sax, S
Key quality aspect: a fundamental step for quality improvement in a resource-poor setting Journal Article
In: Asia Pac J Public Health, vol. 21, no. 4, pp. 477-86, 2009, ISSN: 1010-5395.
@article{RN14543,
title = {Key quality aspect: a fundamental step for quality improvement in a resource-poor setting},
author = {T T Su and S Sax},
doi = {10.1177/1010539509342433},
issn = {1010-5395},
year = {2009},
date = {2009-01-01},
journal = {Asia Pac J Public Health},
volume = {21},
number = {4},
pages = {477-86},
abstract = {The objective of the study is to identify user's perception of key quality aspects of the hospital and its influence on willingness to pay. The study was conducted in 2001 in Dhading District Hospital, Nepal. This was a descriptive, cross-sectional study design using quantitative and qualitative methods: questionnaire exit interview and focus group discussions with inpatients and outpatients, focus group discussion with service providers, and key informant interviews. The research identified attitude, technical and interpersonal skills of health personnel, availability of drugs and services as important quality aspects to be improved. Users were motivated to use this hospital and were ready to pay if they received proper treatment from skilled and communicative staff. This study highlights the importance of identifying the quality factors important to service users as a first step in improving quality. For the users within this study, this meant improving attitude, interpersonal skills, and technical skills of service personnel.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Gan, C Y; Low, Y Y; Etoh, T; Hayashi, M; Komiyama, K; Kam, T S
Leuconicines A-G and (-)-eburnamaline, biologically active strychnan and eburnan alkaloids from Leuconotis Journal Article
In: J Nat Prod, vol. 72, no. 12, pp. 2098-103, 2009, ISSN: 0163-3864.
@article{RN16026,
title = {Leuconicines A-G and (-)-eburnamaline, biologically active strychnan and eburnan alkaloids from Leuconotis},
author = {C Y Gan and Y Y Low and T Etoh and M Hayashi and K Komiyama and T S Kam},
doi = {10.1021/np900576b},
issn = {0163-3864},
year = {2009},
date = {2009-01-01},
journal = {J Nat Prod},
volume = {72},
number = {12},
pages = {2098-103},
abstract = {Seven new indole alkaloids of the Strychnos type, leuconicines A-G (1-7), and a new eburnan alkaloid, (-)-eburnamaline (8), were isolated from the stem-bark extract of two Malayan Leuconotis species. The structures of these alkaloids were established using NMR and MS analysis and in the case of 8 also by partial synthesis. Alkaloids 1-5 reversed multidrug resistance in vincristine-resistant KB cells.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Gan, C Y; Robinson, W T; Etoh, T; Hayashi, M; Komiyama, K; Kam, T S
Leucophyllidine, a cytotoxic bisindole alkaloid constituted from the union of an eburnan and a new vinylquinoline alkaloid Journal Article
In: Org Lett, vol. 11, no. 17, pp. 3962-5, 2009, ISSN: 1523-7052.
@article{RN16029,
title = {Leucophyllidine, a cytotoxic bisindole alkaloid constituted from the union of an eburnan and a new vinylquinoline alkaloid},
author = {C Y Gan and W T Robinson and T Etoh and M Hayashi and K Komiyama and T S Kam},
doi = {10.1021/ol9016172},
issn = {1523-7052},
year = {2009},
date = {2009-01-01},
journal = {Org Lett},
volume = {11},
number = {17},
pages = {3962-5},
abstract = {A cytotoxic bisindole alkaloid possessing an unprecedented structure constituted from the union of an eburnan half and a novel vinylquinoline alkaloid has been isolated from Leuconotis griffithii. The structure was established by analysis of the spectroscopic data and confirmed by X-ray diffraction analysis. A possible biogenetic pathway to the novel quinolinic coupling partner is presented from an Aspidosperma precursor.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Yip, C H; Taib, N A; Tan, G H; Ng, K L; Yoong, B K; Choo, W Y
Predictors of axillary lymph node metastases in breast cancer: is there a role for minimal axillary surgery? Journal Article
In: World J Surg, vol. 33, no. 1, pp. 54-7, 2009, ISSN: 0364-2313 (Print) 0364-2313.
@article{RN820,
title = {Predictors of axillary lymph node metastases in breast cancer: is there a role for minimal axillary surgery?},
author = {C H Yip and N A Taib and G H Tan and K L Ng and B K Yoong and W Y Choo},
doi = {10.1007/s00268-008-9782-7},
issn = {0364-2313 (Print)
0364-2313},
year = {2009},
date = {2009-01-01},
journal = {World J Surg},
volume = {33},
number = {1},
pages = {54-7},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Dahlui, M; Hishamshah, M I; Rahman, A J; Aljunid, S M
Quality of life in transfusion-dependent thalassaemia patients on desferrioxamine treatment Journal Article
In: Singapore Med J, vol. 50, no. 8, pp. 794-9, 2009, ISSN: 0037-5675 (Print) 0037-5675.
@article{RN13810,
title = {Quality of life in transfusion-dependent thalassaemia patients on desferrioxamine treatment},
author = {M Dahlui and M I Hishamshah and A J Rahman and S M Aljunid},
issn = {0037-5675 (Print)
0037-5675},
year = {2009},
date = {2009-01-01},
journal = {Singapore Med J},
volume = {50},
number = {8},
pages = {794-9},
abstract = {INTRODUCTION: The quality of life of transfusion-dependent thalassaemia patients is affected by the disease itself and iron overload complications from repeated blood transfusion. Desferrioxamine has been used to remove the excess iron, resulting in decreased mortality and morbidity. In Malaysia, a significant proportion of the transfusion-dependent thalassaemia patients are not prescribed desferrioxamine, due to its high cost, especially as it is not subsidized by the government. The aim of this study was to measure the quality of life of thalassaemia patients on desferrioxamine treatment. METHODS: A cross-sectional study was performed on all transfusion-dependent thalassaemia patients on follow-up at two tertiary hospitals in Kuala Lumpur, Malaysia, in 2005. Quality-of-life scores were measured by using the translated MOS SF-36 questionnaires, while diseases related to iron overload complications were obtained from the medical records. Use of desferrioxamine was elicited through interviews and validated by drug records. Quality-adjusted life-years (QALYs) presented were formulated from residual life-years and quality-of-life scores. RESULTS: A total of 112 transfusion-dependent thalassaemia patients were recruited, with 54 (48 percent) and 58 (52 percent) patients on sub-optimum and optimum desferrioxamine treatments, respectively. QALYs were higher in patients on optimum desferrioxamine (9.04, standard deviation [SD] 2.46) than patients on sub-optimum desferrioxamine (5.12, SD 2.51). QALYs were associated with the level of serum ferritin, iron overload complications and total family income. CONCLUSION: Optimum desferrioxamine usage reduces iron overload complications and provides a better quality of life.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Noran, N H; Izzuna, M G; Bulgiba, A M; Mimiwati, Z; Ayu, S M
Severity of visual impairment and depression among elderly Malaysians Journal Article
In: Asia Pac J Public Health, vol. 21, no. 1, pp. 43-50, 2009, ISSN: 1010-5395 (Print) 1010-5395 (Linking).
@article{RN13320,
title = {Severity of visual impairment and depression among elderly Malaysians},
author = {N H Noran and M G Izzuna and A M Bulgiba and Z Mimiwati and S M Ayu},
url = {http://www.ncbi.nlm.nih.gov/pubmed/19124335},
doi = {10.1177/1010539508327353},
issn = {1010-5395 (Print)
1010-5395 (Linking)},
year = {2009},
date = {2009-01-01},
journal = {Asia Pac J Public Health},
volume = {21},
number = {1},
pages = {43-50},
abstract = {OBJECTIVE: This study aimed at evaluating the relationship between severity of visual impairment and depression among elderly Malaysians attending an eye clinic. METHODS: This was a cross-sectional study. The study population included patients, aged\>or=60 years who attended the Eye Clinic in University Malaya Medical Centre. Exposure measurement was based on ophthalmologic examinations by an ophthalmologist. Data on outcome were measured using the Geriatric Depression Scale. RESULTS: After adjusting for important confounders, severity of visual impairment either having low vision or blind were independent risk factors of depression. The odds of developing depression among elderly with low vision were 2 times more than those with normal vision, and elderly who were blind had almost 5 times the odds to be depressed compared with those having normal vision. CONCLUSION: Findings from this study suggest a positive relationship between the severity of visual impairment and depression among elderly Malaysians.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Misliza, A; Ayu, S Mas
SOCIODEMOGRAPHIC AND LIFESTYLE FACTORS AS THE RISK OF DIABETIC FOOT ULCER IN THE UNIVERSITY OF MALAYA MEDICAL CENTRE Journal Article
In: JUMMEC: Journal of Health and Translational Medicine (Formerly known as Journal of the University of Malaya Medical Centre), no. 1, pp. 15-21%V 12, 2009, ISSN: 2289-392X.
@article{RN772,
title = {SOCIODEMOGRAPHIC AND LIFESTYLE FACTORS AS THE RISK OF DIABETIC FOOT ULCER IN THE UNIVERSITY OF MALAYA MEDICAL CENTRE},
author = {A Misliza and S Mas Ayu},
url = {https://ejournal.um.edu.my/index.php/jummec/article/view/4613},
issn = {2289-392X},
year = {2009},
date = {2009-01-01},
journal = {JUMMEC: Journal of Health and Translational Medicine (Formerly known as Journal of the University of Malaya Medical Centre)},
number = {1},
pages = {15-21%V 12},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Tan, P C; Vallikkannu, N; Suguna, S; Quek, K F; Hassan, J
Transvaginal sonography of cervical length and Bishop score as predictors of successful induction of term labor: the effect of parity Journal Article
In: Clin Exp Obstet Gynecol, vol. 36, no. 1, pp. 35-9, 2009, ISSN: 0390-6663 (Print) 0390-6663.
@article{RN16035,
title = {Transvaginal sonography of cervical length and Bishop score as predictors of successful induction of term labor: the effect of parity},
author = {P C Tan and N Vallikkannu and S Suguna and K F Quek and J Hassan},
issn = {0390-6663 (Print)
0390-6663},
year = {2009},
date = {2009-01-01},
journal = {Clin Exp Obstet Gynecol},
volume = {36},
number = {1},
pages = {35-9},
abstract = {OBJECTIVE: To evaluate the predictive value for successful labor induction of transvaginal ultrasound (TVS) of cervical length according to parity. METHOD: TVS of the cervix was performed before term labor induction. Induction was considered successful if vaginal delivery was achieved within 24 hours; 231 women were available for final analysis. RESULTS: Analysis of the receiver operator characteristics curve showed an optimal cut-off for cervical length of \< or = 20 mm for successful induction. Following multivariate logistic regression analysis, a sonographic short cervix (AOR 5.6; p \< 0.001) was an independent predictor of successful induction but not a favorable Bishop score (p = 0.47). Among multiparas with a short cervix, positive and negative predictive values for successful induction were 98% (95% CI 90-100%) and 21% (95% CI 13%-32%) and among nulliparas, predictive values were 69% (95% CI 53%-82%) and 77% (95% CI 64%-87%) respectively. CONCLUSION: In nulliparas, cervical length can usefully predict labor induction outcome.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}