1.
Al-Sadat, N; Misau, A Y; Zarihah, Z; Maznah, D; Tin, Su Tin
Adolescent tobacco use and health in Southeast Asia Journal Article
In: Asia Pac J Public Health, vol. 22, no. 3 Suppl, pp. 175s-180s, 2010, ISSN: 1010-5395.
@article{RN14538,
title = {Adolescent tobacco use and health in Southeast Asia},
author = {N Al-Sadat and A Y Misau and Z Zarihah and D Maznah and Su Tin Tin},
url = {http://aph.sagepub.com/content/22/3_suppl/175S.full.pdf},
doi = {10.1177/1010539510372835},
issn = {1010-5395},
year = {2010},
date = {2010-01-01},
journal = {Asia Pac J Public Health},
volume = {22},
number = {3 Suppl},
pages = {175s-180s},
abstract = {The use of tobacco by adolescents is a major public health concern worldwide. There are 1.2 billion smokers globally, of which more than 50% are young people. The Southeast Asian countries have about 600 million tobacco smokers within the global burden of tobacco users. Most smokers begin at early stage of life and persist through adulthood. Malaysia alone has about 5 million smokers, 20% of whom are younger than 18 years old. Many factors are implicated in the continuous rising trend of tobacco use among adolescents in Southeast Asia. A triad of family, environmental, and individual factors synergistically acts to motivate adolescents toward smoking. This article discusses the current trends of tobacco use and implications of increasing rise in adolescent smoking in the Southeast Asia region.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The use of tobacco by adolescents is a major public health concern worldwide. There are 1.2 billion smokers globally, of which more than 50% are young people. The Southeast Asian countries have about 600 million tobacco smokers within the global burden of tobacco users. Most smokers begin at early stage of life and persist through adulthood. Malaysia alone has about 5 million smokers, 20% of whom are younger than 18 years old. Many factors are implicated in the continuous rising trend of tobacco use among adolescents in Southeast Asia. A triad of family, environmental, and individual factors synergistically acts to motivate adolescents toward smoking. This article discusses the current trends of tobacco use and implications of increasing rise in adolescent smoking in the Southeast Asia region.
2.
Tai, M L; Goh, K L; Mohd-Taib, S H; Rampal, S; Mahadeva, S
Anthropometric, biochemical and clinical assessment of malnutrition in Malaysian patients with advanced cirrhosis Journal Article
In: Nutr J, vol. 9, pp. 27, 2010, ISSN: 1475-2891.
@article{RN16018,
title = {Anthropometric, biochemical and clinical assessment of malnutrition in Malaysian patients with advanced cirrhosis},
author = {M L Tai and K L Goh and S H Mohd-Taib and S Rampal and S Mahadeva},
doi = {10.1186/1475-2891-9-27},
issn = {1475-2891},
year = {2010},
date = {2010-01-01},
journal = {Nutr J},
volume = {9},
pages = {27},
abstract = {BACKGROUND: There is limited data on the nutritional status of Asian patients with various aetiologies of cirrhosis. This study aimed to determine the prevalence of malnutrition and to compare nutritional differences between various aetiologies. METHODOLOGY: A cross-sectional study of adult patients with decompensated cirrhosis was conducted. Nutritional status was assessed using standard anthropometry, serum visceral proteins and subjective global assessment (SGA). RESULTS: Thirty six patients (mean age 59.8 +/- 12.8 years; 66.7% males; 41.6% viral hepatitis; Child-Pugh C 55.6%) with decompensated cirrhosis were recruited. Malnutrition was prevalent in 18 (50%) patients and the mean caloric intake was low at 15.2 kcal/kg/day. SGA grade C, as compared to SGA grade B, demonstrated significantly lower anthropometric values in males (BMI 18.1 +/- 1.6 vs 26.3 +/- 3.5 kg/m2, p \< 0.0001; MAMC 19.4 +/- 1.5 vs 24.5 +/- 3.6 cm},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
BACKGROUND: There is limited data on the nutritional status of Asian patients with various aetiologies of cirrhosis. This study aimed to determine the prevalence of malnutrition and to compare nutritional differences between various aetiologies. METHODOLOGY: A cross-sectional study of adult patients with decompensated cirrhosis was conducted. Nutritional status was assessed using standard anthropometry, serum visceral proteins and subjective global assessment (SGA). RESULTS: Thirty six patients (mean age 59.8 +/- 12.8 years; 66.7% males; 41.6% viral hepatitis; Child-Pugh C 55.6%) with decompensated cirrhosis were recruited. Malnutrition was prevalent in 18 (50%) patients and the mean caloric intake was low at 15.2 kcal/kg/day. SGA grade C, as compared to SGA grade B, demonstrated significantly lower anthropometric values in males (BMI 18.1 +/- 1.6 vs 26.3 +/- 3.5 kg/m2, p < 0.0001; MAMC 19.4 +/- 1.5 vs 24.5 +/- 3.6 cm
3.
Gan, C Y; Low, Y Y; Robinson, W T; Komiyama, K; Kam, T S
Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis Journal Article
In: Phytochemistry, vol. 71, no. 11-12, pp. 1365-70, 2010, ISSN: 0031-9422.
@article{RN16020,
title = {Aspidospermatan-aspidospermatan and eburnane-sarpagine bisindole alkaloids from Leuconotis},
author = {C Y Gan and Y Y Low and W T Robinson and K Komiyama and T S Kam},
doi = {10.1016/j.phytochem.2010.05.015},
issn = {0031-9422},
year = {2010},
date = {2010-01-01},
journal = {Phytochemistry},
volume = {71},
number = {11-12},
pages = {1365-70},
abstract = {Leucofoline and leuconoline, representing the first members of the aspidospermatan-aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Leucofoline and leuconoline, representing the first members of the aspidospermatan-aspidospermatan and eburnane-sarpagine subclasses of the bisindole alkaloids, respectively, were isolated from the Malayan Leuconotis griffithii. The structures of these bisindole alkaloids were established using NMR and MS analysis, and in the case of leuconoline, confirmed by X-ray diffraction analysis. Both alkaloids showed weak cytotoxicity towards human KB cells.
4.
Misau, Y A; Al-Sadat, N; Gerei, A B
Brain-drain and health care delivery in developing countries Journal Article
In: J Public Health Afr, vol. 1, no. 1, pp. e6, 2010, ISSN: 2038-9922 (Print) 2038-9922.
@article{RN16013,
title = {Brain-drain and health care delivery in developing countries},
author = {Y A Misau and N Al-Sadat and A B Gerei},
doi = {10.4081/jphia.2010.e6},
issn = {2038-9922 (Print)
2038-9922},
year = {2010},
date = {2010-01-01},
journal = {J Public Health Afr},
volume = {1},
number = {1},
pages = {e6},
abstract = {Migration of health workers 'Brain drain' is defined as the movement of health personnel in search of a better standard of living and life quality, higher salaries, access to advanced technology and more stable political conditions in different places worldwide. The debate about migration of health workers from the developing to the developed world has remained pertinent for decades now. Regardless of the push and pull factors, migration of health care workers from developing countries to developed ones, have done more harm than good on the health care deliveries in the developing countries. This article reviews the literature on the effects of cross-border migration of health care professionals.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Migration of health workers 'Brain drain' is defined as the movement of health personnel in search of a better standard of living and life quality, higher salaries, access to advanced technology and more stable political conditions in different places worldwide. The debate about migration of health workers from the developing to the developed world has remained pertinent for decades now. Regardless of the push and pull factors, migration of health care workers from developing countries to developed ones, have done more harm than good on the health care deliveries in the developing countries. This article reviews the literature on the effects of cross-border migration of health care professionals.
5.
Moy, FM; Hoe, VCW; Tan, CPL; Rosmawati, M
CARDIOVASCULAR RISKS AMONG SHIFT AND NON-SHIFT WORKERS IN A PUBLIC MEDICAL CENTRE IN KUALA LUMPUR Journal Article
In: JUMMEC: Journal of Health and Translational Medicine (Formerly known as Journal of the University of Malaya Medical Centre), vol. 13, no. 1, pp. 45-49, 2010, ISSN: 2289-392X.
@article{RN774,
title = {CARDIOVASCULAR RISKS AMONG SHIFT AND NON-SHIFT WORKERS IN A PUBLIC MEDICAL CENTRE IN KUALA LUMPUR},
author = {FM Moy and VCW Hoe and CPL Tan and M Rosmawati},
url = {https://ejournal.um.edu.my/index.php/jummec/article/view/4634},
issn = {2289-392X},
year = {2010},
date = {2010-01-01},
journal = {JUMMEC: Journal of Health and Translational Medicine (Formerly known as Journal of the University of Malaya Medical Centre)},
volume = {13},
number = {1},
pages = {45-49},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
6.
Bulgiba, A M; Dahlui, M
Developing global public health links in southeast Asia Journal Article
In: Asia Pac J Public Health, vol. 22, no. 3 Suppl, pp. 14S-18S, 2010, ISSN: 1941-2479 (Electronic) 1010-5395 (Linking).
@article{RN14642,
title = {Developing global public health links in southeast Asia},
author = {A M Bulgiba and M Dahlui},
url = {https://www.ncbi.nlm.nih.gov/pubmed/20566528},
doi = {10.1177/1010539510372831},
issn = {1941-2479 (Electronic)
1010-5395 (Linking)},
year = {2010},
date = {2010-01-01},
journal = {Asia Pac J Public Health},
volume = {22},
number = {3 Suppl},
pages = {14S-18S},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
7.
Abdullah, F; Su, T T
Enhancement of the cervical cancer screening program in Malaysia: a qualitative study Journal Article
In: Asian Pac J Cancer Prev, vol. 11, no. 5, pp. 1359-66, 2010, ISSN: 1513-7368 (Print) 1513-7368.
@article{RN14640,
title = {Enhancement of the cervical cancer screening program in Malaysia: a qualitative study},
author = {F Abdullah and T T Su},
issn = {1513-7368 (Print)
1513-7368},
year = {2010},
date = {2010-01-01},
journal = {Asian Pac J Cancer Prev},
volume = {11},
number = {5},
pages = {1359-66},
abstract = {INTRODUCTION: Cervical cancer has long been known as a preventable disease. Yet it still is a prime women's health issue globally. In Malaysia, the current cervical cancer screening program, introduced in the 1960s, has been found to be unsuccessful in terms of Pap smear coverage. The aim of this study is to determine providers perceptives on the program and the feasibility of practicing an organized cervical screening program in Malaysia. METHODS: 11 key informant interviews were conducted with policy makers and health care providers from the Ministry of Health in Malaysia from October 2009 to May 2010. Interviewees' perceptions were explored on current and organized cervical screening program based on their expertise and experience. RESULTS: The results highlighted that the existing cervical screening program in Malaysia faced flaws at all levels that failed to reduce cervical cancer morbidity and mortality. The identified weaknesses were poor acceptance by women, lack of commitment by health care providers, nature of the program, an improper follow-up system, limited resources and other competing needs. Complementarily, all interviewees perceived an organized cervical screening program as an alternative approach both feasible and acceptable by women and government to practice in Malaysia. CONCLUSION: Better screening coverage depends on an effective screening program that incorporates a behaviour-based strategy. A new program should be focused in the policy-making context to improve screening coverage and to effectively combat cervical cancer.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
INTRODUCTION: Cervical cancer has long been known as a preventable disease. Yet it still is a prime women's health issue globally. In Malaysia, the current cervical cancer screening program, introduced in the 1960s, has been found to be unsuccessful in terms of Pap smear coverage. The aim of this study is to determine providers perceptives on the program and the feasibility of practicing an organized cervical screening program in Malaysia. METHODS: 11 key informant interviews were conducted with policy makers and health care providers from the Ministry of Health in Malaysia from October 2009 to May 2010. Interviewees' perceptions were explored on current and organized cervical screening program based on their expertise and experience. RESULTS: The results highlighted that the existing cervical screening program in Malaysia faced flaws at all levels that failed to reduce cervical cancer morbidity and mortality. The identified weaknesses were poor acceptance by women, lack of commitment by health care providers, nature of the program, an improper follow-up system, limited resources and other competing needs. Complementarily, all interviewees perceived an organized cervical screening program as an alternative approach both feasible and acceptable by women and government to practice in Malaysia. CONCLUSION: Better screening coverage depends on an effective screening program that incorporates a behaviour-based strategy. A new program should be focused in the policy-making context to improve screening coverage and to effectively combat cervical cancer.
8.
Mahadeva, S; Yadav, H; Rampal, S; Everett, S M; Goh, K L
Ethnic variation, epidemiological factors and quality of life impairment associated with dyspepsia in urban Malaysia Journal Article
In: Aliment Pharmacol Ther, vol. 31, no. 10, pp. 1141-51, 2010, ISSN: 0269-2813.
@article{RN16024,
title = {Ethnic variation, epidemiological factors and quality of life impairment associated with dyspepsia in urban Malaysia},
author = {S Mahadeva and H Yadav and S Rampal and S M Everett and K L Goh},
doi = {10.1111/j.1365-2036.2010.04270.x},
issn = {0269-2813},
year = {2010},
date = {2010-01-01},
journal = {Aliment Pharmacol Ther},
volume = {31},
number = {10},
pages = {1141-51},
abstract = {BACKGROUND: The role of ethnicity in the development of dyspepsia remains uncertain. AIMS: To examine the epidemiology of dyspepsia in a multi-ethnic Asian population and its impact on health-related quality of life (HRQOL). METHODS: A cross-sectional survey was conducted in a representative urban population in Kuala Lumpur, Malaysia. RESULTS: A total of 2039 adults (mean +/- s.d. age: 40.5 +/- 11.8 years, males 44.2%, ethnicity: Malays 45.3%, Chinese 38.0% and Indians 13.1%, tertiary education level 62%, professional employment 47.7% and median monthly income USD 850.00) were interviewed. Dyspepsia was prevalent in 496 (24.3%) adults. Independent predictors for dyspepsia, explored by logistic regression, were identified as: Malay (OR 2.17, 95% CI = 1.57-2.99) and Indian (OR 1.59, 95% CI = 1.03-2.45) ethnicity, heavy chilli intake (OR 2.35, 95% CI = 1.15-4.80), use of regular analgesia (OR 3.51, 95% CI = 2.54-4.87) and chronic illness (OR 1.67, 95% CI = 1.22-2.28). HRQOL was assessed with the EQ-5D and significantly lower scores were noted in dyspeptics compared with healthy controls (0.85 +/- 0.17 vs. 0.95 +/- 0.12, P \< 0.0001). CONCLUSION: Ethnicity, in addition to recognized epidemiological factors, is a risk factor for dyspepsia in an urban multi-racial Asian population.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
BACKGROUND: The role of ethnicity in the development of dyspepsia remains uncertain. AIMS: To examine the epidemiology of dyspepsia in a multi-ethnic Asian population and its impact on health-related quality of life (HRQOL). METHODS: A cross-sectional survey was conducted in a representative urban population in Kuala Lumpur, Malaysia. RESULTS: A total of 2039 adults (mean +/- s.d. age: 40.5 +/- 11.8 years, males 44.2%, ethnicity: Malays 45.3%, Chinese 38.0% and Indians 13.1%, tertiary education level 62%, professional employment 47.7% and median monthly income USD 850.00) were interviewed. Dyspepsia was prevalent in 496 (24.3%) adults. Independent predictors for dyspepsia, explored by logistic regression, were identified as: Malay (OR 2.17, 95% CI = 1.57-2.99) and Indian (OR 1.59, 95% CI = 1.03-2.45) ethnicity, heavy chilli intake (OR 2.35, 95% CI = 1.15-4.80), use of regular analgesia (OR 3.51, 95% CI = 2.54-4.87) and chronic illness (OR 1.67, 95% CI = 1.22-2.28). HRQOL was assessed with the EQ-5D and significantly lower scores were noted in dyspeptics compared with healthy controls (0.85 +/- 0.17 vs. 0.95 +/- 0.12, P < 0.0001). CONCLUSION: Ethnicity, in addition to recognized epidemiological factors, is a risk factor for dyspepsia in an urban multi-racial Asian population.
9.
Alibrahim, O A; Al-Sadat, N; Elawad, N A
Gender and risk of depression in Saudi Arabia, a systematic review and meta-analysis Journal Article
In: J Public Health Afr, vol. 1, no. 1, pp. e7, 2010, ISSN: 2038-9922 (Print) 2038-9922.
@article{RN16007,
title = {Gender and risk of depression in Saudi Arabia, a systematic review and meta-analysis},
author = {O A Alibrahim and N Al-Sadat and N A Elawad},
doi = {10.4081/jphia.2010.e7},
issn = {2038-9922 (Print)
2038-9922},
year = {2010},
date = {2010-01-01},
journal = {J Public Health Afr},
volume = {1},
number = {1},
pages = {e7},
abstract = {Depression is one of the leading causes of mortality and morbidity worldwide. In the year 2000 depression accounted for 4.4% of the global disability adjusted life years (DALYs). The Kingdom of Saudi Arabia (KSA) has a population of 28 million people and is one of the countries experiencing demographic transition in its population structure. Improvements in socioeconomic status have been shown to be associated with increased chronic diseases including chronic mental diseases like depression, but still there is no comprehensive review summarizing the various reports currently existing in the literature. Although individual studies within Saudi Arabia have reported prevalence rates and risks, the quality of such studies need to be subjected to rigorous assessment and their findings pooled to give combined weighted evidence that will provide basis for targeted intervention. Pooled risks have the advantage of adjusting inherent variations within sampled populations and therefore providing more reliable estimates even though there are concerns about possible magnification of smaller individual risks.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Depression is one of the leading causes of mortality and morbidity worldwide. In the year 2000 depression accounted for 4.4% of the global disability adjusted life years (DALYs). The Kingdom of Saudi Arabia (KSA) has a population of 28 million people and is one of the countries experiencing demographic transition in its population structure. Improvements in socioeconomic status have been shown to be associated with increased chronic diseases including chronic mental diseases like depression, but still there is no comprehensive review summarizing the various reports currently existing in the literature. Although individual studies within Saudi Arabia have reported prevalence rates and risks, the quality of such studies need to be subjected to rigorous assessment and their findings pooled to give combined weighted evidence that will provide basis for targeted intervention. Pooled risks have the advantage of adjusting inherent variations within sampled populations and therefore providing more reliable estimates even though there are concerns about possible magnification of smaller individual risks.
10.
Choong, L P; Taib, N A; Rampal, S; Saad, M; Bustam, A Z; Yip, C H
High tumour stage and margin clearance are still important prognostic factors for post-mastectomy locoregional recurrence in Malaysia Journal Article
In: Asian Pac J Cancer Prev, vol. 11, no. 5, pp. 1409-16, 2010, ISSN: 1513-7368.
@article{RN16002,
title = {High tumour stage and margin clearance are still important prognostic factors for post-mastectomy locoregional recurrence in Malaysia},
author = {L P Choong and N A Taib and S Rampal and M Saad and A Z Bustam and C H Yip},
issn = {1513-7368},
year = {2010},
date = {2010-01-01},
journal = {Asian Pac J Cancer Prev},
volume = {11},
number = {5},
pages = {1409-16},
abstract = {BACKGROUND: Locoregional recurrence after mastectomy for breast cancer may predict distant recurrence and mortality. This study examined the pattern and rates of post-mastectomy locoregional recurrence (PMLRR), survival outcome and prognostic factors for isolated PMLRR (ILR) in a breast cancer cohort in University of Malaya Medical Center (UMMC). METHODS: We studied 522 patients who underwent mastectomy between 1998 and 2002 and followed them up until 2008. We defined PMLRR as recurrence to the axilla, supraclavicular nodes and or chest wall. ILR was defined as PMLRR occurring as an isolated event. Prognostic factors for locoregional recurrence were determined using the Cox proportional hazards regression model. RESULTS: The overall PMLRR rate was 16.4%. ILR developed in 42 of 522 patients (8.0%). Within this subgroup, 25 (59.5%) remained disease free after treatment while 17 (40.5%) suffered disease progression. Univariate analyses identified race, age, size, stage, margin involvement, lymph node involvement, grade, lymphovascular invasion and ER status as probable prognostic factors for ILR. Cox regression resulted in only stage III disease and margin involvement as independent prognostic factors. The hazard of ILR was 2.5 times higher when the margins were involved compared to when they were clear (aHRR 2.5; 95% CI 1.3 to 5.0). Similarly, compared with stage I those with Stage II (aHRR 2.1; 95%CI 0.6 to 6.8) and stage III (aHRR 4.6; 95%CI 1.4 to 15.9) had worse prognosis for ILR. CONCLUSION: Margin involvement and stage III disease were identified to be independent prognostic factors for ILR. Close follow-up of high risk patients and prompt treatment of locoregional recurrence were recommended.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
BACKGROUND: Locoregional recurrence after mastectomy for breast cancer may predict distant recurrence and mortality. This study examined the pattern and rates of post-mastectomy locoregional recurrence (PMLRR), survival outcome and prognostic factors for isolated PMLRR (ILR) in a breast cancer cohort in University of Malaya Medical Center (UMMC). METHODS: We studied 522 patients who underwent mastectomy between 1998 and 2002 and followed them up until 2008. We defined PMLRR as recurrence to the axilla, supraclavicular nodes and or chest wall. ILR was defined as PMLRR occurring as an isolated event. Prognostic factors for locoregional recurrence were determined using the Cox proportional hazards regression model. RESULTS: The overall PMLRR rate was 16.4%. ILR developed in 42 of 522 patients (8.0%). Within this subgroup, 25 (59.5%) remained disease free after treatment while 17 (40.5%) suffered disease progression. Univariate analyses identified race, age, size, stage, margin involvement, lymph node involvement, grade, lymphovascular invasion and ER status as probable prognostic factors for ILR. Cox regression resulted in only stage III disease and margin involvement as independent prognostic factors. The hazard of ILR was 2.5 times higher when the margins were involved compared to when they were clear (aHRR 2.5; 95% CI 1.3 to 5.0). Similarly, compared with stage I those with Stage II (aHRR 2.1; 95%CI 0.6 to 6.8) and stage III (aHRR 4.6; 95%CI 1.4 to 15.9) had worse prognosis for ILR. CONCLUSION: Margin involvement and stage III disease were identified to be independent prognostic factors for ILR. Close follow-up of high risk patients and prompt treatment of locoregional recurrence were recommended.
11.
Wong, L P
In: Singapore Med J, vol. 51, no. 10, pp. 790-5, 2010, ISSN: 0037-5675 (Print) 0037-5675.
@article{RN14533,
title = {Information needs, preferred educational messages and channel of delivery, and opinion on strategies to promote organ donation: a multicultural perspective},
author = {L P Wong},
issn = {0037-5675 (Print)
0037-5675},
year = {2010},
date = {2010-01-01},
journal = {Singapore Med J},
volume = {51},
number = {10},
pages = {790-5},
abstract = {INTRODUCTION: This study assessed the information needs, preferred educational messages and channels of delivery, as well as opinions on strategies to promote organ donation. It aimed to provide insight into a culturally sensitive public education campaign to encourage organ donation in diverse ethnic communities in Asia, namely the Malays, Chinese and Indians. METHODS: A total of 17 focus group discussions with 105 participants were conducted between September and December 2008. The participants were members of the general public aged 18 to 60 years, who were recruited through convenient sampling in the Klang Valley area of Malaysia. RESULTS: Across ethnic groups, there was a general concern about the mistreatment of the deceased's body in the organ procurement process. The Chinese and Indian participants wanted assurance that the body would be treated with respect and care. The Muslims wanted assurance that the handling of a Muslim's body would follow the rules and regulations of the Islamic faith. The most important information requested by the Muslim participants was whether cadaveric donation is permissible in Islam. A lack of national public education and promotion of organ donation was noted. All the three ethnic groups, especially the Malays, required community and religious leaders for support, encouragement and involvement, as sociocultural influences play a significant role in the willingness to donate organs. CONCLUSION: The pronounced ethnic differences in information needs suggest that culturally sensitive public educational messages are required. Organ donation and transplantation organisations should work closely with community and religious organisations to address the sociocultural barriers identified.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
INTRODUCTION: This study assessed the information needs, preferred educational messages and channels of delivery, as well as opinions on strategies to promote organ donation. It aimed to provide insight into a culturally sensitive public education campaign to encourage organ donation in diverse ethnic communities in Asia, namely the Malays, Chinese and Indians. METHODS: A total of 17 focus group discussions with 105 participants were conducted between September and December 2008. The participants were members of the general public aged 18 to 60 years, who were recruited through convenient sampling in the Klang Valley area of Malaysia. RESULTS: Across ethnic groups, there was a general concern about the mistreatment of the deceased's body in the organ procurement process. The Chinese and Indian participants wanted assurance that the body would be treated with respect and care. The Muslims wanted assurance that the handling of a Muslim's body would follow the rules and regulations of the Islamic faith. The most important information requested by the Muslim participants was whether cadaveric donation is permissible in Islam. A lack of national public education and promotion of organ donation was noted. All the three ethnic groups, especially the Malays, required community and religious leaders for support, encouragement and involvement, as sociocultural influences play a significant role in the willingness to donate organs. CONCLUSION: The pronounced ethnic differences in information needs suggest that culturally sensitive public educational messages are required. Organ donation and transplantation organisations should work closely with community and religious organisations to address the sociocultural barriers identified.
12.
Gan, C Y; Etoh, T; Hayashi, M; Komiyama, K; Kam, T S
Leucoridines A-D, cytotoxic Strychnos-Strychnos bisindole alkaloids from Leuconotis Journal Article
In: J Nat Prod, vol. 73, no. 6, pp. 1107-11, 2010, ISSN: 0163-3864.
@article{RN16021,
title = {Leucoridines A-D, cytotoxic Strychnos-Strychnos bisindole alkaloids from Leuconotis},
author = {C Y Gan and T Etoh and M Hayashi and K Komiyama and T S Kam},
doi = {10.1021/np1001187},
issn = {0163-3864},
year = {2010},
date = {2010-01-01},
journal = {J Nat Prod},
volume = {73},
number = {6},
pages = {1107-11},
abstract = {Four new bisindole alkaloids of the Strychnos-Strychnos type, leucoridines A-D (1-4), were isolated from the stem-bark extract of Leuconotis griffithii. Alkaloids 1-4 showed moderate cytotoxicity against drug-sensitive and vincristine-resistant human KB cells.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Four new bisindole alkaloids of the Strychnos-Strychnos type, leucoridines A-D (1-4), were isolated from the stem-bark extract of Leuconotis griffithii. Alkaloids 1-4 showed moderate cytotoxicity against drug-sensitive and vincristine-resistant human KB cells.
13.
Hairi, N N; Cumming, R G; Naganathan, V; Handelsman, D J; Couteur, D G Le; Creasey, H; Waite, L M; Seibel, M J; Sambrook, P N
In: J Am Geriatr Soc, vol. 58, no. 11, pp. 2055-62, 2010, ISSN: 0002-8614.
@article{RN14535,
title = {Loss of muscle strength, mass (sarcopenia), and quality (specific force) and its relationship with functional limitation and physical disability: the Concord Health and Ageing in Men Project},
author = {N N Hairi and R G Cumming and V Naganathan and D J Handelsman and D G Le Couteur and H Creasey and L M Waite and M J Seibel and P N Sambrook},
url = {http://onlinelibrary.wiley.com/doi/10.1111/j.1532-5415.2010.03145.x/abstract},
doi = {10.1111/j.1532-5415.2010.03145.x},
issn = {0002-8614},
year = {2010},
date = {2010-01-01},
journal = {J Am Geriatr Soc},
volume = {58},
number = {11},
pages = {2055-62},
abstract = {OBJECTIVES: To determine the association between loss of muscle strength, mass, and quality and functional limitation and physical disability in older men. DESIGN: Cross-sectional study of older men participating in the Concord Health and Ageing in Men Project (CHAMP). SETTING: Elderly men living in a defined geographical region in Sydney, Australia. PARTICIPANTS: One thousand seven hundred five community-dwelling men aged 70 and older who participated in the baseline assessments of CHAMP. MEASUREMENTS: Upper and lower extremity strength were measured using dynamometers for grip and quadriceps strength. Appendicular skeletal lean mass was assessed using dual X-ray absorptiometry. Muscle quality was defined as the ratio of strength to mass in upper and lower extremities. For each parameter, subjects in the lowest 20% of the distribution were defined as below normal. Functional limitation was assessed according to self-report and objective lower extremity performance measures. Physical disability was measured according to self-report questionnaire. RESULTS: After adjusting for important confounders, the prevalence ratio (PR) for poor quadriceps strength and self-reported functional limitation was 1.91 (95% confidence interval (CI) = 1.10-2.40); for performance-based functional limitation the PR was 1.81 (95% CI = 1.45-2.24). The adjusted PR for poor grip strength and physical disability in instrumental activities of daily living (IADLs) was 1.37 (95% CI = 1.20-1.56). The adjusted PR for low skeletal lean mass (adjusted for fat mass) and physical disability in basic activities of daily living was 2.08 (95% CI = 1.37-3.15). For muscle quality, the PR for lower extremity specific force and functional limitation and physical disability was stronger than upper extremity specific force. CONCLUSION: Muscle strength is the single best measure of age-related muscle change and is associated with physical disability in IADLs and functional limitation.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
OBJECTIVES: To determine the association between loss of muscle strength, mass, and quality and functional limitation and physical disability in older men. DESIGN: Cross-sectional study of older men participating in the Concord Health and Ageing in Men Project (CHAMP). SETTING: Elderly men living in a defined geographical region in Sydney, Australia. PARTICIPANTS: One thousand seven hundred five community-dwelling men aged 70 and older who participated in the baseline assessments of CHAMP. MEASUREMENTS: Upper and lower extremity strength were measured using dynamometers for grip and quadriceps strength. Appendicular skeletal lean mass was assessed using dual X-ray absorptiometry. Muscle quality was defined as the ratio of strength to mass in upper and lower extremities. For each parameter, subjects in the lowest 20% of the distribution were defined as below normal. Functional limitation was assessed according to self-report and objective lower extremity performance measures. Physical disability was measured according to self-report questionnaire. RESULTS: After adjusting for important confounders, the prevalence ratio (PR) for poor quadriceps strength and self-reported functional limitation was 1.91 (95% confidence interval (CI) = 1.10-2.40); for performance-based functional limitation the PR was 1.81 (95% CI = 1.45-2.24). The adjusted PR for poor grip strength and physical disability in instrumental activities of daily living (IADLs) was 1.37 (95% CI = 1.20-1.56). The adjusted PR for low skeletal lean mass (adjusted for fat mass) and physical disability in basic activities of daily living was 2.08 (95% CI = 1.37-3.15). For muscle quality, the PR for lower extremity specific force and functional limitation and physical disability was stronger than upper extremity specific force. CONCLUSION: Muscle strength is the single best measure of age-related muscle change and is associated with physical disability in IADLs and functional limitation.
14.
Anbori, A; Ghani, S N; Yadav, H; Daher, A M; Su, T T
Patient satisfaction and loyalty to the private hospitals in Sana'a, Yemen Journal Article
In: Int J Qual Health Care, vol. 22, no. 4, pp. 310-5, 2010, ISSN: 1353-4505.
@article{RN13779,
title = {Patient satisfaction and loyalty to the private hospitals in Sana'a, Yemen},
author = {A Anbori and S N Ghani and H Yadav and A M Daher and T T Su},
url = {http://intqhc.oxfordjournals.org/content/intqhc/22/4/310.full.pdf},
doi = {10.1093/intqhc/mzq029},
issn = {1353-4505},
year = {2010},
date = {2010-01-01},
journal = {Int J Qual Health Care},
volume = {22},
number = {4},
pages = {310-5},
abstract = {OBJECTIVE: To evaluate patients' satisfaction and loyalty to private hospitals and to identify factors influencing patient loyalty. DESIGN: A cross-sectional, population-based study was conducted between May and September of 2005. SETTING: Sana'a, the capital city of the Republic of Yemen. PARTICIPANTS: Eight hundred and nineteen respondents who were admitted for at least 1 day in a private hospital within last 6 months from the date of interview. MAIN OUTCOME MEASURES: The scores on the modified SERVQUAL market research instrument including six domains (tangibility, reliability, responsiveness, assurance, empathy and cost) that identify perceptions of service quality. In addition, the respondents were asked whether or not they would return to the same facility when they need future medical care (loyalty). RESULTS: Loyalty was higher among females [odds ratio (OR) = 1.44; P \< 0.05], among those reporting higher reliability scores (OR = 1.24; P \< 0.01), higher assurance scores (OR = 1.2; P \< 0.01) and higher empathy scores (OR = 1.13; P \< 0.05) and also among those reporting higher cost (OR = 1.15; P\<0.05). No significant association was found between patient loyalty and, tangibility and responsiveness score. CONCLUSIONS: Improvements are required to achieve high-quality healthcare services in the private hospitals in Yemen and increase loyalty among patients. Findings from this study could inform private sector healthcare development in low- and middle-income countries.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
OBJECTIVE: To evaluate patients' satisfaction and loyalty to private hospitals and to identify factors influencing patient loyalty. DESIGN: A cross-sectional, population-based study was conducted between May and September of 2005. SETTING: Sana'a, the capital city of the Republic of Yemen. PARTICIPANTS: Eight hundred and nineteen respondents who were admitted for at least 1 day in a private hospital within last 6 months from the date of interview. MAIN OUTCOME MEASURES: The scores on the modified SERVQUAL market research instrument including six domains (tangibility, reliability, responsiveness, assurance, empathy and cost) that identify perceptions of service quality. In addition, the respondents were asked whether or not they would return to the same facility when they need future medical care (loyalty). RESULTS: Loyalty was higher among females [odds ratio (OR) = 1.44; P < 0.05], among those reporting higher reliability scores (OR = 1.24; P < 0.01), higher assurance scores (OR = 1.2; P < 0.01) and higher empathy scores (OR = 1.13; P < 0.05) and also among those reporting higher cost (OR = 1.15; P<0.05). No significant association was found between patient loyalty and, tangibility and responsiveness score. CONCLUSIONS: Improvements are required to achieve high-quality healthcare services in the private hospitals in Yemen and increase loyalty among patients. Findings from this study could inform private sector healthcare development in low- and middle-income countries.
15.
Hairi, N N; Bulgiba, A; Cumming, R G; Naganathan, V; Mudla, I
In: BMC Public Health, vol. 10, pp. 492, 2010, ISSN: 1471-2458.
@article{RN14537,
title = {Prevalence and correlates of physical disability and functional limitation among community dwelling older people in rural Malaysia, a middle income country},
author = {N N Hairi and A Bulgiba and R G Cumming and V Naganathan and I Mudla},
url = {http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933720/pdf/1471-2458-10-492.pdf},
doi = {10.1186/1471-2458-10-492},
issn = {1471-2458},
year = {2010},
date = {2010-01-01},
journal = {BMC Public Health},
volume = {10},
pages = {492},
abstract = {BACKGROUND: The prevalence and correlates of physical disability and functional limitation among older people have been studied in many developed countries but not in a middle income country such as Malaysia. The present study investigated the epidemiology of physical disability and functional limitation among older people in Malaysia and compares findings to other countries. METHODS: A population-based cross sectional study was conducted in Alor Gajah, Malacca. Seven hundred and sixty five older people aged 60 years and above underwent tests of functional limitation (Tinetti Performance Oriented Mobility Assessment Tool). Data were also collected for self reported activities of daily living (ADL) using the Barthel Index (ten items). To compare prevalence with other studies, ADL disability was also defined using six basic ADL's (eating, bathing, dressing, transferring, toileting and walking) and five basic ADL's (eating, bathing, dressing, transferring and toileting). RESULTS: Ten, six and five basic ADL disability was reported by 24.7% (95% CI 21.6-27.9), 14.4% (95% CI 11.9-17.2) and 10.6% (95% CI 8.5-13.1), respectively. Functional limitation was found in 19.5% (95% CI 16.8-22.5) of participants. Variables independently associated with 10 item ADL disability physical disability, were advanced age (\> or = 75 years: prevalence ratio (PR) 7.9; 95% CI 4.8-12.9), presence of diabetes (PR 1.8; 95% CI 1.4-2.3), stroke (PR 1.5; 95% CI 1.1-2.2), depressive symptomology (PR 1.3; 95% CI 1.1-1.8) and visual impairment (blind: PR 2.0; 95% CI 1.1-3.6). Advancing age (\> or = 75 years: PR 3.0; 95% CI 1.7-5.2) being female (PR 2.7; 95% CI 1.2-6.1), presence of arthritis (PR 1.6; 95% CI 1.2-2.1) and depressive symptomology (PR 2.0; 95% CI 1.5-2.7) were significantly associated with functional limitation. CONCLUSIONS: The prevalence of physical disability and functional limitation among older Malaysians appears to be much higher than in developed countries but is comparable to developing countries. Associations with socio-demographic and other health related variables were consistent with other studies.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
BACKGROUND: The prevalence and correlates of physical disability and functional limitation among older people have been studied in many developed countries but not in a middle income country such as Malaysia. The present study investigated the epidemiology of physical disability and functional limitation among older people in Malaysia and compares findings to other countries. METHODS: A population-based cross sectional study was conducted in Alor Gajah, Malacca. Seven hundred and sixty five older people aged 60 years and above underwent tests of functional limitation (Tinetti Performance Oriented Mobility Assessment Tool). Data were also collected for self reported activities of daily living (ADL) using the Barthel Index (ten items). To compare prevalence with other studies, ADL disability was also defined using six basic ADL's (eating, bathing, dressing, transferring, toileting and walking) and five basic ADL's (eating, bathing, dressing, transferring and toileting). RESULTS: Ten, six and five basic ADL disability was reported by 24.7% (95% CI 21.6-27.9), 14.4% (95% CI 11.9-17.2) and 10.6% (95% CI 8.5-13.1), respectively. Functional limitation was found in 19.5% (95% CI 16.8-22.5) of participants. Variables independently associated with 10 item ADL disability physical disability, were advanced age (> or = 75 years: prevalence ratio (PR) 7.9; 95% CI 4.8-12.9), presence of diabetes (PR 1.8; 95% CI 1.4-2.3), stroke (PR 1.5; 95% CI 1.1-2.2), depressive symptomology (PR 1.3; 95% CI 1.1-1.8) and visual impairment (blind: PR 2.0; 95% CI 1.1-3.6). Advancing age (> or = 75 years: PR 3.0; 95% CI 1.7-5.2) being female (PR 2.7; 95% CI 1.2-6.1), presence of arthritis (PR 1.6; 95% CI 1.2-2.1) and depressive symptomology (PR 2.0; 95% CI 1.5-2.7) were significantly associated with functional limitation. CONCLUSIONS: The prevalence of physical disability and functional limitation among older Malaysians appears to be much higher than in developed countries but is comparable to developing countries. Associations with socio-demographic and other health related variables were consistent with other studies.
16.
Masilamani, R
Recent development in occupational health services in Malaysia Journal Article
In: Malaysian Journal of Public Health Medicine, vol. 10, no. 2, pp. 1-5, 2010.
@article{RN804,
title = {Recent development in occupational health services in Malaysia},
author = {R Masilamani},
year = {2010},
date = {2010-01-01},
journal = {Malaysian Journal of Public Health Medicine},
volume = {10},
number = {2},
pages = {1-5},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
17.
Mahadeva, S; Yadav, H; Rampal, S; Goh, K L
Risk factors associated with dyspepsia in a rural Asian population and its impact on quality of life Journal Article
In: Am J Gastroenterol, vol. 105, no. 4, pp. 904-12, 2010, ISSN: 0002-9270.
@article{RN16023,
title = {Risk factors associated with dyspepsia in a rural Asian population and its impact on quality of life},
author = {S Mahadeva and H Yadav and S Rampal and K L Goh},
doi = {10.1038/ajg.2010.26},
issn = {0002-9270},
year = {2010},
date = {2010-01-01},
journal = {Am J Gastroenterol},
volume = {105},
number = {4},
pages = {904-12},
abstract = {OBJECTIVES: The epidemiology and impact of dyspepsia in rural Asia remains uncertain. We aimed to determine the prevalence epidemiology and impact of dyspepsia in a rural Malaysian community. METHODS: A door-to-door survey was conducted in a representative rural population in Malaysia. Dyspepsia was defined according to the Rome II criteria, and health-related quality of life (HRQOL) was assessed using the Euroqol (EQ-5D) instrument. RESULTS: Of 2,260 adults, 2,000 (88.5%) completed the survey. The mean age of respondents was 40.4+/-15.3 years, 62.7% were women, 79.0% were ethnic Malays, 8.4% had been educated up to the tertiary level, 49.7% were unemployed, and 63.4% resided in village-type housing with 49.1% having \>8 residents per household. Dyspepsia was prevalent in 292 (14.6%) adults, and they had lower mean EQ-5D utility scores compared with healthy controls (0.91+/-0.17 vs. 0.97+/-0.08, P\<0.0001). Dyspepsia was found to be associated with female gender (15.8 vs. 12.7% males},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
OBJECTIVES: The epidemiology and impact of dyspepsia in rural Asia remains uncertain. We aimed to determine the prevalence epidemiology and impact of dyspepsia in a rural Malaysian community. METHODS: A door-to-door survey was conducted in a representative rural population in Malaysia. Dyspepsia was defined according to the Rome II criteria, and health-related quality of life (HRQOL) was assessed using the Euroqol (EQ-5D) instrument. RESULTS: Of 2,260 adults, 2,000 (88.5%) completed the survey. The mean age of respondents was 40.4+/-15.3 years, 62.7% were women, 79.0% were ethnic Malays, 8.4% had been educated up to the tertiary level, 49.7% were unemployed, and 63.4% resided in village-type housing with 49.1% having >8 residents per household. Dyspepsia was prevalent in 292 (14.6%) adults, and they had lower mean EQ-5D utility scores compared with healthy controls (0.91+/-0.17 vs. 0.97+/-0.08, P<0.0001). Dyspepsia was found to be associated with female gender (15.8 vs. 12.7% males
18.
Loh, S Y; Yip, C H; Packer, T; Quek, K F
Self management pilot study on women with breast cancer: lessons learnt in Malaysia Journal Article
In: Asian Pac J Cancer Prev, vol. 11, no. 5, pp. 1293-9, 2010, ISSN: 1513-7368.
@article{RN16004,
title = {Self management pilot study on women with breast cancer: lessons learnt in Malaysia},
author = {S Y Loh and C H Yip and T Packer and K F Quek},
issn = {1513-7368},
year = {2010},
date = {2010-01-01},
journal = {Asian Pac J Cancer Prev},
volume = {11},
number = {5},
pages = {1293-9},
abstract = {OBJECTIVE: With increasing survival rates, breast cancer is now considered a chronic condition necessitating innovative care to meet the long-term needs of survivors. This paper presents the findings of a pilot study on self-management for women diagnosed with breast cancer and their implications for Asian health care providers. METHODS: A pre-test/ post-test pilot study was conducted to gain preliminary insights into program feasibility and barriers to participation, and to provide justification for a larger trial. RESULTS: The study found the 4 week self-management program feasible and acceptable, with a favourable trend in quality of life. The recruitment barriers ranged from competing medical appointments, uncollaborative health providers, linguistic barriers and social-household concerns. Supporting facilitators identified were family, health professionals and fellow participants ("buddies"). Lessons from the study are discussed with regard to Asian health providers. CONCLUSION: There is preliminary evidence that self management is a workable and potentially useful model even in an Asians entrenched-hierarchical medical model of care. The initial challenge was breaking down barriers in acceptancee of a collaborative stance. A clinical trial is now warranted to gather more evidence.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
OBJECTIVE: With increasing survival rates, breast cancer is now considered a chronic condition necessitating innovative care to meet the long-term needs of survivors. This paper presents the findings of a pilot study on self-management for women diagnosed with breast cancer and their implications for Asian health care providers. METHODS: A pre-test/ post-test pilot study was conducted to gain preliminary insights into program feasibility and barriers to participation, and to provide justification for a larger trial. RESULTS: The study found the 4 week self-management program feasible and acceptable, with a favourable trend in quality of life. The recruitment barriers ranged from competing medical appointments, uncollaborative health providers, linguistic barriers and social-household concerns. Supporting facilitators identified were family, health professionals and fellow participants ("buddies"). Lessons from the study are discussed with regard to Asian health providers. CONCLUSION: There is preliminary evidence that self management is a workable and potentially useful model even in an Asians entrenched-hierarchical medical model of care. The initial challenge was breaking down barriers in acceptancee of a collaborative stance. A clinical trial is now warranted to gather more evidence.
19.
Ayu, S M; Lai, L R; Chan, Y F; Hatim, A; Hairi, N N; Ayob, A; Sam, I C
Seroprevalence survey of Chikungunya virus in Bagan Panchor, Malaysia Journal Article
In: Am J Trop Med Hyg, vol. 83, no. 6, pp. 1245-8, 2010, ISSN: 0002-9637.
@article{RN14532,
title = {Seroprevalence survey of Chikungunya virus in Bagan Panchor, Malaysia},
author = {S M Ayu and L R Lai and Y F Chan and A Hatim and N N Hairi and A Ayob and I C Sam},
url = {http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990039/pdf/tropmed-83-1245.pdf},
doi = {10.4269/ajtmh.2010.10-0279},
issn = {0002-9637},
year = {2010},
date = {2010-01-01},
journal = {Am J Trop Med Hyg},
volume = {83},
number = {6},
pages = {1245-8},
abstract = {In 2006, an outbreak of Chikungunya virus (CHIKV) of the Asian genotype affected over 200 people in Bagan Panchor village in Malaysia. One year later, a post-outbreak survey was performed to determine attack rate, asymptomatic rate, and post-infection sequelae. Findings were compared with recent CHIKV outbreaks of the Central/East African genotype. A total of 180 residents were interviewed for acute symptoms and post-infection physical quality of life and depressive symptoms. Sera from 72 residents were tested for CHIKV neutralizing antibodies. The estimated attack rate was 55.6%, and 17.5% of infected residents were asymptomatic. Arthralgia was reported up to 3 months after infection, but there were no reports of long-term functional dependence or depression. Symptomatic and seropositive residents were significantly more likely to live in the area with the most dense housing and commercial activities. CHIKV had a high attack rate and considerable clinical impact during the Bagan Panchor outbreak.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
In 2006, an outbreak of Chikungunya virus (CHIKV) of the Asian genotype affected over 200 people in Bagan Panchor village in Malaysia. One year later, a post-outbreak survey was performed to determine attack rate, asymptomatic rate, and post-infection sequelae. Findings were compared with recent CHIKV outbreaks of the Central/East African genotype. A total of 180 residents were interviewed for acute symptoms and post-infection physical quality of life and depressive symptoms. Sera from 72 residents were tested for CHIKV neutralizing antibodies. The estimated attack rate was 55.6%, and 17.5% of infected residents were asymptomatic. Arthralgia was reported up to 3 months after infection, but there were no reports of long-term functional dependence or depression. Symptomatic and seropositive residents were significantly more likely to live in the area with the most dense housing and commercial activities. CHIKV had a high attack rate and considerable clinical impact during the Bagan Panchor outbreak.
20.
Rosnawati, M R; Moe, H; Masilamani, R; Darus, A
The Bahasa Melayu version of the Nursing Stress Scale among nurses: a reliability study in Malaysia Journal Article
In: Asia Pac J Public Health, vol. 22, no. 4, pp. 501-6, 2010, ISSN: 1010-5395.
@article{RN16012,
title = {The Bahasa Melayu version of the Nursing Stress Scale among nurses: a reliability study in Malaysia},
author = {M R Rosnawati and H Moe and R Masilamani and A Darus},
doi = {10.1177/1010539510380560},
issn = {1010-5395},
year = {2010},
date = {2010-01-01},
journal = {Asia Pac J Public Health},
volume = {22},
number = {4},
pages = {501-6},
abstract = {The Nursing Stress Scale (NSS) has been shown to be a valid and reliable instrument to assess occupational stressors among nurses. The NSS, which was previously used in the English version, was translated and back-translated into Bahasa Melayu. This study was conducted to assess the reliability of the Bahasa Melayu version of the NSS among nurses for future studies in this country. The reliability of the NSS was assessed after its readministration to 30 nurses with a 2-week interval. The Spearman coefficient was calculated to assess its stability. The internal consistency was measured through 4 measures: Cronbach's alpha, Spearman-Brown, Guttman split-half, and standardized item alpha coefficients. The total response rate was 70%. Test-retest reliability showed remarkable stability (Spearman's rho exceeded .70). All 4 measures of internal consistency among items indicated a satisfactory level (coefficients in the range of .68 to .87). In conclusion, the Bahasa Melayu version of the NSS is a reliable and useful instrument for measuring the possible stressors at the workplace among nurses.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The Nursing Stress Scale (NSS) has been shown to be a valid and reliable instrument to assess occupational stressors among nurses. The NSS, which was previously used in the English version, was translated and back-translated into Bahasa Melayu. This study was conducted to assess the reliability of the Bahasa Melayu version of the NSS among nurses for future studies in this country. The reliability of the NSS was assessed after its readministration to 30 nurses with a 2-week interval. The Spearman coefficient was calculated to assess its stability. The internal consistency was measured through 4 measures: Cronbach's alpha, Spearman-Brown, Guttman split-half, and standardized item alpha coefficients. The total response rate was 70%. Test-retest reliability showed remarkable stability (Spearman's rho exceeded .70). All 4 measures of internal consistency among items indicated a satisfactory level (coefficients in the range of .68 to .87). In conclusion, the Bahasa Melayu version of the NSS is a reliable and useful instrument for measuring the possible stressors at the workplace among nurses.
21.
Kuppusamy, S; Faizal, N; Quek, K F; Razack, A H; Dublin, N
In: World J Urol, vol. 28, no. 6, pp. 673-6, 2010, ISSN: 0724-4983.
@article{RN16015,
title = {The efficacy of periprostatic local anaesthetic infiltration in transrectal ultrasound biopsy of prostate: a prospective randomised control study},
author = {S Kuppusamy and N Faizal and K F Quek and A H Razack and N Dublin},
doi = {10.1007/s00345-010-0578-7},
issn = {0724-4983},
year = {2010},
date = {2010-01-01},
journal = {World J Urol},
volume = {28},
number = {6},
pages = {673-6},
abstract = {OBJECTIVE: It is still uncertain as to which form of anaesthesia is the optimum. We conducted a study to identify the best location and optimum volume of anaesthetic agent in order to achieve best pain relief and cooperation from our patients. We also assessed the need for local anaesthetic gel for probe lubrication and if the number of cores during biopsy makes a difference in the pain score. MATERIALS AND METHOD: A total of 386 patients were randomised into 4 groups i.e. no anaesthesia (Group A), 10 cc 1% Lignocaine at apical region of prostate (Group B), 5 cc 1% Lignocaine each at both bases (Group C) and lastly, 4 cc at apex and 3 cc each at both bases (Group D). Pain assessment was performed using the 10-point Visual Analog Scale after the procedure with regard to probe insertion and during the biopsy. RESULTS: The groups were comparable in number and mean age. Group B recorded the lowest mean pain score of 2.59. Comparative analysis showed significant pain relief when comparing Group B vs. Group A (P = 0.001). The other groups were not as effective. The overall mean pain score for the probe insertion and the number of cores during biopsy was also not significant. CONCLUSIONS: We suggest that a 10 cc 1% Lignocaine infiltration at the apical region of the prostate be used to obtain best pain relief during this procedure. Plain lubricant jelly is sufficient for probe insertion. There is no need to alter the anaesthetic requirement if number of cores is increased.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
OBJECTIVE: It is still uncertain as to which form of anaesthesia is the optimum. We conducted a study to identify the best location and optimum volume of anaesthetic agent in order to achieve best pain relief and cooperation from our patients. We also assessed the need for local anaesthetic gel for probe lubrication and if the number of cores during biopsy makes a difference in the pain score. MATERIALS AND METHOD: A total of 386 patients were randomised into 4 groups i.e. no anaesthesia (Group A), 10 cc 1% Lignocaine at apical region of prostate (Group B), 5 cc 1% Lignocaine each at both bases (Group C) and lastly, 4 cc at apex and 3 cc each at both bases (Group D). Pain assessment was performed using the 10-point Visual Analog Scale after the procedure with regard to probe insertion and during the biopsy. RESULTS: The groups were comparable in number and mean age. Group B recorded the lowest mean pain score of 2.59. Comparative analysis showed significant pain relief when comparing Group B vs. Group A (P = 0.001). The other groups were not as effective. The overall mean pain score for the probe insertion and the number of cores during biopsy was also not significant. CONCLUSIONS: We suggest that a 10 cc 1% Lignocaine infiltration at the apical region of the prostate be used to obtain best pain relief during this procedure. Plain lubricant jelly is sufficient for probe insertion. There is no need to alter the anaesthetic requirement if number of cores is increased.
22.
Moy, F M; Bulgiba, A
The modified NCEP ATP III criteria maybe better than the IDF criteria in diagnosing Metabolic Syndrome among Malays in Kuala Lumpur Journal Article
In: BMC Public Health, vol. 10, pp. 678, 2010, ISSN: 1471-2458.
@article{RN14534,
title = {The modified NCEP ATP III criteria maybe better than the IDF criteria in diagnosing Metabolic Syndrome among Malays in Kuala Lumpur},
author = {F M Moy and A Bulgiba},
doi = {10.1186/1471-2458-10-678},
issn = {1471-2458},
year = {2010},
date = {2010-01-01},
journal = {BMC Public Health},
volume = {10},
pages = {678},
abstract = {BACKGROUND: Metabolic Syndrome is associated with increased risk for type 2 diabetes and cardiovascular diseases. However, different diagnostic criteria have been recommended by different expert groups. In Malaysia, there is a lack of research comparing these different diagnostic criteria. Therefore, it is our aim to study the concordance between the IDF and the modified NCEP ATP III definitions of Metabolic Syndrome among a Malay cohort in Kuala Lumpur; and to demonstrate if all participants have the same cardiometabolic risks. METHODS: This was an analytical cross sectional study. Ethics approval was obtained and informed consent was given by all participants. Anthropometric measurements, blood pressure, fasting blood glucose and lipid profile were taken following standard protocols. RESULTS: Metabolic Syndrome was diagnosed in 41.4% and 38.2% participants using the modified NCEP and IDF criteria respectively. Among those diagnosed with Metabolic Syndrome by modified NCEP, 7.6% were missed by the IDF criteria. Participants diagnosed by the modified NCEP criteria had lower BMI and waist circumference but had higher cardiometabolic risks than those diagnosed with both criteria. Their blood pressure, glucose, total cholesterol and triglyceride were more adverse than the IDF group. This demonstrated that central obesity may not be a prerequisite for the development of increased cardiometabolic risks within this Malay cohort. CONCLUSION: Metabolic syndrome is common in this Malay cohort regardless of the criterion used. The modified NCEP ATP III criteria may be more suitable in diagnosis of metabolic syndrome for this Malay cohort.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
BACKGROUND: Metabolic Syndrome is associated with increased risk for type 2 diabetes and cardiovascular diseases. However, different diagnostic criteria have been recommended by different expert groups. In Malaysia, there is a lack of research comparing these different diagnostic criteria. Therefore, it is our aim to study the concordance between the IDF and the modified NCEP ATP III definitions of Metabolic Syndrome among a Malay cohort in Kuala Lumpur; and to demonstrate if all participants have the same cardiometabolic risks. METHODS: This was an analytical cross sectional study. Ethics approval was obtained and informed consent was given by all participants. Anthropometric measurements, blood pressure, fasting blood glucose and lipid profile were taken following standard protocols. RESULTS: Metabolic Syndrome was diagnosed in 41.4% and 38.2% participants using the modified NCEP and IDF criteria respectively. Among those diagnosed with Metabolic Syndrome by modified NCEP, 7.6% were missed by the IDF criteria. Participants diagnosed by the modified NCEP criteria had lower BMI and waist circumference but had higher cardiometabolic risks than those diagnosed with both criteria. Their blood pressure, glucose, total cholesterol and triglyceride were more adverse than the IDF group. This demonstrated that central obesity may not be a prerequisite for the development of increased cardiometabolic risks within this Malay cohort. CONCLUSION: Metabolic syndrome is common in this Malay cohort regardless of the criterion used. The modified NCEP ATP III criteria may be more suitable in diagnosis of metabolic syndrome for this Malay cohort.
23.
Chong, H Y; Taib, N A; Rampal, S; Saad, M; Bustam, A Z; Yip, C H
Treatment options for locally advanced breast cancer--experience in an Asian tertiary hospital Journal Article
In: Asian Pac J Cancer Prev, vol. 11, no. 4, pp. 913-7, 2010, ISSN: 1513-7368.
@article{RN16005,
title = {Treatment options for locally advanced breast cancer--experience in an Asian tertiary hospital},
author = {H Y Chong and N A Taib and S Rampal and M Saad and A Z Bustam and C H Yip},
issn = {1513-7368},
year = {2010},
date = {2010-01-01},
journal = {Asian Pac J Cancer Prev},
volume = {11},
number = {4},
pages = {913-7},
abstract = {BACKGROUND: Locally advanced breast cancer (LABC) is characterized by the presence of a large primary tumour (\>5 cm) associated with or without skin or chest-wall involvement (T4) or with fixed (matted) axillary lymph nodes in the absence of any evidence of distant metastases. These cancers are classified as stage IIIA and IIIB according to the AJCC Staging System. Treatment of choice involves combinations of surgery, chemotherapy, radiotherapy and/or hormonal therapy. Current guidelines recommend primary surgery or neoadjuvant therapy followed by surgery. The primary objective of this study was to compare the outcome of LABC patients subjected to neoadjuvant chemotherapy before surgery and those who underwent surgery as the primary treatment and to determine prognostic predictors. Secondary objectives were to evaluate the response after neoadjuvant therapy and to determine the treatment compliance rate. METHODS: This retrospective study of Stage III breast cancer patients was conducted over a 5 year period from 1998 to 2002. The survival data were obtained from the National Registry of Births and Deaths with the end-point of the study in April 2006. The Kaplan Meier method was applied for survival analysis. Cox regression analysis by stepwise selection was performed to identify important prognostic factors. RESULTS: Out of a 155 evaluable patients, 74 (47.7%) had primary surgery, 62 (40%) had neoadjuvant chemotherapy, 10 patients (6.5%) were given Tamoxifen as the primary treatment, while 9 patients (5.8%) defaulted any form of treatment. After neoadjuvant chemotherapy, 9 patients defaulted further treatment, leaving 53 evaluable patients. Out of these 53 evaluable patients, 5 patients (9.4%) had complete pathological response, 5 (9.4%) a complete clinical response, and 26 (49.1%) had partial response after neoadjuvant chemotherapy. The 5-year survival in the primary surgery group was 56.7 % compared to 44.7% in the neoadjuvant chemotherapy group (p\<0.01). The important prognostic factors were race, size of tumour, nodal status, estrogen receptor status and response to neoadjuvant chemotherapy. CONCLUSION: Patients who had primary surgery had better survival than those who underwent neoadjuvant chemotherapy, which may be due to bias in the selection of patients for neoadjuvant chemotherapy. Out of a total of 155 patients, 25.1% defaulted part of the treatment, or did not receive optimal treatment, emphasizing the importance of psychosocial support and counselling for this group of patients.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
BACKGROUND: Locally advanced breast cancer (LABC) is characterized by the presence of a large primary tumour (>5 cm) associated with or without skin or chest-wall involvement (T4) or with fixed (matted) axillary lymph nodes in the absence of any evidence of distant metastases. These cancers are classified as stage IIIA and IIIB according to the AJCC Staging System. Treatment of choice involves combinations of surgery, chemotherapy, radiotherapy and/or hormonal therapy. Current guidelines recommend primary surgery or neoadjuvant therapy followed by surgery. The primary objective of this study was to compare the outcome of LABC patients subjected to neoadjuvant chemotherapy before surgery and those who underwent surgery as the primary treatment and to determine prognostic predictors. Secondary objectives were to evaluate the response after neoadjuvant therapy and to determine the treatment compliance rate. METHODS: This retrospective study of Stage III breast cancer patients was conducted over a 5 year period from 1998 to 2002. The survival data were obtained from the National Registry of Births and Deaths with the end-point of the study in April 2006. The Kaplan Meier method was applied for survival analysis. Cox regression analysis by stepwise selection was performed to identify important prognostic factors. RESULTS: Out of a 155 evaluable patients, 74 (47.7%) had primary surgery, 62 (40%) had neoadjuvant chemotherapy, 10 patients (6.5%) were given Tamoxifen as the primary treatment, while 9 patients (5.8%) defaulted any form of treatment. After neoadjuvant chemotherapy, 9 patients defaulted further treatment, leaving 53 evaluable patients. Out of these 53 evaluable patients, 5 patients (9.4%) had complete pathological response, 5 (9.4%) a complete clinical response, and 26 (49.1%) had partial response after neoadjuvant chemotherapy. The 5-year survival in the primary surgery group was 56.7 % compared to 44.7% in the neoadjuvant chemotherapy group (p<0.01). The important prognostic factors were race, size of tumour, nodal status, estrogen receptor status and response to neoadjuvant chemotherapy. CONCLUSION: Patients who had primary surgery had better survival than those who underwent neoadjuvant chemotherapy, which may be due to bias in the selection of patients for neoadjuvant chemotherapy. Out of a total of 155 patients, 25.1% defaulted part of the treatment, or did not receive optimal treatment, emphasizing the importance of psychosocial support and counselling for this group of patients.
24.
Khambalia, A Z; Seen, L S
Trends in overweight and obese adults in Malaysia (1996-2009): a systematic review Journal Article
In: Obes Rev, vol. 11, no. 6, pp. 403-12, 2010, ISSN: 1467-789X (Electronic) 1467-7881 (Linking).
@article{RN11836,
title = {Trends in overweight and obese adults in Malaysia (1996-2009): a systematic review},
author = {A Z Khambalia and L S Seen},
url = {http://onlinelibrary.wiley.com/doi/10.1111/j.1467-789X.2010.00728.x/abstract},
doi = {10.1111/j.1467-789X.2010.00728.x},
issn = {1467-789X (Electronic)
1467-7881 (Linking)},
year = {2010},
date = {2010-01-01},
journal = {Obes Rev},
volume = {11},
number = {6},
pages = {403-12},
abstract = {Like other nations experiencing rapid industrialization, urbanization and a nutrition transition, there is concern in Malaysia of a possible escalation in the prevalence of overweight and obesity. In 1996, the National Health and Morbidity Survey reported a 16.6% and 4.4% prevalence of overweight and obesity, respectively. In the following decade, there have been several national and community surveys on overweight and obesity in Malaysia. The objective of this systematic review is to describe the trend from 1996 to 2009 in the prevalence of overweight and obesity in adults in Malaysia nationally and by gender, age and race. Results indicate that there has been a small rise in overweight adults in the years 1996, 2003 and 2006 (20.7%, 26.7% and 29.1%) and a much more dramatic increase in obesity in 1996, 2003, 2004 and 2006 (5.5%, 12.2%, 12.3% and 14.0%). Evidence showed a greater risk for overweight and obesity among women compared with men. Based on the highest-quality studies, overweight and obesity levels were highest among adults 40-59 years old. Overweight levels were highest among Indians, followed by Malays, Chinese and Aboriginals, with less consistency across studies on the order of risk or obesity by ethnicity.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
Like other nations experiencing rapid industrialization, urbanization and a nutrition transition, there is concern in Malaysia of a possible escalation in the prevalence of overweight and obesity. In 1996, the National Health and Morbidity Survey reported a 16.6% and 4.4% prevalence of overweight and obesity, respectively. In the following decade, there have been several national and community surveys on overweight and obesity in Malaysia. The objective of this systematic review is to describe the trend from 1996 to 2009 in the prevalence of overweight and obesity in adults in Malaysia nationally and by gender, age and race. Results indicate that there has been a small rise in overweight adults in the years 1996, 2003 and 2006 (20.7%, 26.7% and 29.1%) and a much more dramatic increase in obesity in 1996, 2003, 2004 and 2006 (5.5%, 12.2%, 12.3% and 14.0%). Evidence showed a greater risk for overweight and obesity among women compared with men. Based on the highest-quality studies, overweight and obesity levels were highest among adults 40-59 years old. Overweight levels were highest among Indians, followed by Malays, Chinese and Aboriginals, with less consistency across studies on the order of risk or obesity by ethnicity.
25.
Rampal, S; Rampal, L; Rahmat, R; Zain, A M; Yap, Y G; Mohamed, M; Taha, M
Variation in the prevalence, awareness, and control of diabetes in a multiethnic population: a nationwide population study in Malaysia Journal Article
In: Asia Pac J Public Health, vol. 22, no. 2, pp. 194-202, 2010, ISSN: 1010-5395.
@article{RN16033,
title = {Variation in the prevalence, awareness, and control of diabetes in a multiethnic population: a nationwide population study in Malaysia},
author = {S Rampal and L Rampal and R Rahmat and A M Zain and Y G Yap and M Mohamed and M Taha},
doi = {10.1177/1010539509334816},
issn = {1010-5395},
year = {2010},
date = {2010-01-01},
journal = {Asia Pac J Public Health},
volume = {22},
number = {2},
pages = {194-202},
abstract = {The purpose of this study was to determine the association between different ethnic groups and the prevalence, awareness, and control of diabetes in Malaysia. A population-based cross-sectional study using multistage sampling was conducted in Malaysia. Diabetes is defined as having a fasting blood glucose \> or =7 mmol/L or a self-reported diabetic on treatment. Among the 7683 respondents aged \> or =30 years, the prevalence of diabetes mellitus was 15.2% (95% CI = 14.1, 16.4). Multivariate analysis showed that compared with Malays, Chinese had lower odds (adjusted odds ratio [aOR] 0.71; 95% CI = 0.56, 0.91) and Indians had higher odds of having diabetes (aOR 1.54; 95% CI = 1.20, 1.98). The odds of diabetes increased with age, family history of diabetes, body mass index, and lower education levels. Among those with diabetes mellitus, 45.0% were aware and 42.7% were under treatment. Among treated diabetics, 25.1% had their fasting blood sugar under control. There is a significant association between prevalence of diabetes and different ethnic groups.},
keywords = {},
pubstate = {published},
tppubtype = {article}
}
The purpose of this study was to determine the association between different ethnic groups and the prevalence, awareness, and control of diabetes in Malaysia. A population-based cross-sectional study using multistage sampling was conducted in Malaysia. Diabetes is defined as having a fasting blood glucose > or =7 mmol/L or a self-reported diabetic on treatment. Among the 7683 respondents aged > or =30 years, the prevalence of diabetes mellitus was 15.2% (95% CI = 14.1, 16.4). Multivariate analysis showed that compared with Malays, Chinese had lower odds (adjusted odds ratio [aOR] 0.71; 95% CI = 0.56, 0.91) and Indians had higher odds of having diabetes (aOR 1.54; 95% CI = 1.20, 1.98). The odds of diabetes increased with age, family history of diabetes, body mass index, and lower education levels. Among those with diabetes mellitus, 45.0% were aware and 42.7% were under treatment. Among treated diabetics, 25.1% had their fasting blood sugar under control. There is a significant association between prevalence of diabetes and different ethnic groups.