Breast cancer in a multi-ethnic Asian setting: results from the Singapore-Malaysia hospital-based breast cancer registry.

Breast. 2011 Apr;20 Suppl 2:S75-80. Epub 2011 Feb 12.

Author

Pathy NB, Yip CH, Taib NA, Hartman M, Saxena N, Iau P, Bulgiba AM, Lee SC, Lim SE, Wong JE, Verkooijen HM; Singapore-Malaysia Breast Cancer Working Group.

Institution

Julius Centre University of Malaya, Department of Social and Preventive Medicine, Faculty of Medicine, University of Malaya, Lembah Pantai, Kuala Lumpur, Malaysia. ovenjjay@gmail.com

Abstract

Two hospital-based breast cancer databases (University Malaya Medical Center, Malaysia [n = 1513] and National University Hospital, Singapore [n = 2545]) were merged into a regional registry of breast cancer patients diagnosed between 1990 and 2007. A review of the data found 51% of patients diagnosed before the age of 50 years. and 72% percent of the women were Chinese followed by Malays (16%), Indians (8%), and other races (4%). Median tumor size at presentation was 26 mm and about 25% of patients presented with TNM stage III or IV disease. Most tumors were of ductal histology (87%). Fifty-seven percent of tumors were estrogen receptor positive and 40% were poorly differentiated. Of those patients who had surgery, 70% had mastectomy while 30% had breast conserving surgery. Overall, chemotherapy was administered to 56% of patients and hormonal treatment to 60%. Five-year overall survival was 82.5% in patients with TNM stage 0 to stage II cancer, and 30.2% in those with later stages.

Copyright © 2011 Elsevier Ltd. All rights reserved.

PMID: 21316967 [PubMed - indexed for MEDLINE]


Information

  1. News
  2. Workshops & Short Courses
  3. Research
  4. Publication

Clinics

The Occupational Medicine Clinic is a referral clinic for occupational diseases and is open on every Friday in University Malaya Medical Centre.